ISSN 2673-494X
Two-page Reports on Science

Cuban Sci. 2022, Vol. 3, Issue 1

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Natural Sciences (1 report)

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Cuban Sci. 2022, 3(1): 7–8
Marcelo Marcet-Palacios
Published on 21 Jul 2022 PDF (615K)
“Our efforts to improve a model of the HIV-1 virus structure led us to the development of software to validate hypothetical versions of the HIV-1 matrix shell. In this manuscript we reconstruct a full model of the HIV-1 envelop protein and predict its interaction with a previously published matrix shell structure. The evidence generated suggests a role of the HIV-1 matrix shell in viral entry.”

Cuban Sci. 2020, Vol. 1, Issue 1

Natural Sciences (1 report)

1
Cuban Sci. 2020, 1(1): 19–20
Marcelo Marcet-Palacios
Published on 22 May 2020 PDF (942K)
“The structure of the HIV matrix shell has not been fully elucidated. In this article, I highlight contributions that led to a model composed of adjacent hexagons forming a sphere and mentioned studies that were subsequently impacted. A cross-disciplinary group of students in my lab tested this hypothesis and conclusively demonstrated that this model was incorrect. I provide a summary of our results with emphasis placed on contributions made by students.”