Cuban Sci. 2022, 3(1): 7–8
Published on 21 Jul 2022 PDF (615K)Important validation of 3D models of HIV-1 matrix shells
Marcelo Marcet-Palacios
- Laboratory Research and Biotechnology, Northern Alberta Institute of Technology, Edmonton, Canada
- Alberta Respiratory Medicine, University of Alberta, Edmonton, Canada
“Our efforts to improve a model of the HIV-1 virus structure led us to the development of software to validate hypothetical versions of the HIV-1 matrix shell. In this manuscript we reconstruct a full model of the HIV-1 envelop protein and predict its interaction with a previously published matrix shell structure. The evidence generated suggests a role of the HIV-1 matrix shell in viral entry.”
References
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