“Our efforts to improve a model of the HIV-1 virus structure led us to the development of software to validate hypothetical versions of the HIV-1 matrix shell. In this manuscript we reconstruct a full model of the HIV-1 envelop protein and predict its interaction with a previously published matrix shell structure. The evidence generated suggests a role of the HIV-1 matrix shell in viral entry.”

“A quantum vaccinomics approach was proposed based on the characterization of vector-host-pathogen molecular interactions and the immunological quantum to further advance the design of more effective and safe vaccines.”