“CIMAvax-EGF controls circulating epidermal growth factor (EGF) through a vaccine-induced antibody response, but prolonged administration of mineral-oil adjuvants can cause tissue damage at the injection site and in adjacent areas. We evaluated the humoral immunogenicity and maintenance of anti-EGF antibodies elicited by hydroxyapatite nanoparticle (HANp) systems, showing sustained IgG responses, predominantly IgG1/Th2, and preservation of antibody levels after replacing CIMAvax-EGF maintenance doses with HANp–rhEGF–rP64k.”

“The phylogenetic placement and taxonomic affinities of the fungus Ellisembia coronata, the type species of the genus, were resolved after its recollection on the original host and type locality in Germany. Implications for the systematics of Ellisembia, Sporidesmium and related genera are summarized.”